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Lets talk about what we actually know: The Biology: GLP-1 receptors are expressed throughout the body, including on immune cells, endothelial cells (lining blood vessels), neurons, and adipose tissue

Each location contains subcutaneous adipose tissuethe layer of fat beneath the skinwhich delivers medication into the body's interstitial fluid for absorption

In 2025, Evernorth excluded Wegovy from approximately 22% of employer plans in favor of compounded semaglutide or no coverage at all (Conklin et al., Health Affairs 2025)

Under the Dietary Supplement Health and Education Act (DSHEA), these products are regulated as foods, not medications, and manufacturers cannot legally claim they treat, cure, or prevent disease