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Studies reported that GLP1-RAs improve metabolic and reproductive parameters (such as menstrual regularity) in women with polycystic ovarian syndrome (PCOS), raising the possibility that GLP1-RAs may improve fertility in women with PCOS
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Additionally, the suppression of pro-inflammatory cytokines (e.g., TNF-, IL-6) and inflammatory pathways, including the blocking of NF-B activation [39, 91], contributes to the establishment of an anti-inflammatory environment that can mitigate oxidative stress and inflammation induced muscle protein catabolism, thereby supporting the preservation of SMM and functional capacity [40]
