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This in turn suppresses the efficiency of iron ion uptake by TFR and the iron storage capacity of ferritin, leading to a decrease in intracellular iron ion levels and inhibition of ferroptosis

The targets of area postrema neuronal projections include the rostral ventrolateral medulla (RVLM), with the efferent projections from the RVLM innervating the sympathetic preganglionic neurons (183)