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The VDss is the theoretical volume that a drug needs to be uniformly distributed to produce the same plasma concentration
It should be noted that processes dependent on the adenosylcobalamin cofactor are more numerous and more developed [16,17,18,19], and they also support the transfer of hydrogen between substrates [20,21,22,23,24] after the breaking of the Co- C bond [4, 25,26,27,28,29]
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