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People with diabetes, particularly severe diabetes, tend to lose less weight with GLP-1s than people without diabetes, so microdosing is less likely to be as effective, though their dose should only be increased as they tolerate it. George said that in her professional opinion, microdosing is a potential option for patients with smaller amounts of weight to lose or as a bridge to start, or wean off, regular GLP-1 medications

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The weighted median provides a consistent estimate of the causal effect even when up to 50% of the information comes from genetic variants that are invalid instruments [43]

7d), surpassing the reduction observed in the other groups