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This occurs through altering the concentration of absorbable iron, modulating the intestinal absorption surface area, and affecting the expression of genes related to iron metabolism ( 4.2 Regulation of ferroptosis by gut microbiota metabolites 4.2.1 Short-chain fatty acids Short-chain fatty acids (SCFAs)mainly acetate, propionate, and butyratehave been shown to exert multiple beneficial effects in letrozole-induced PCOS rat models, such as improving lipid metabolism and mitigating oxidative stress and inflammation

Mulcahy, Up-regulation of the human gamma-glutamylcysteine synthetase regulatory subunit gene involves binding of Nrf-2 to an electrophile responsive element

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About this article Cite this article Giugliano, D., Longo, M., Signoriello, S