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Description

Evidence is provided that asymptomatic meningococcal carriage on the nasopharyngeal mucosal surface is facilitated by localized hypermutation in contingency genes, which, together with horizontal gene transfer, affects the expression of a plethora of surface determinants involved in meningococcal adhesion, metabolism, intracellular survival, intra-species and interspecies competition, and escape of immune response (Green et al., 2020)

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