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The STEP 1 trial, published in the New England Journal of Medicine, studied once-weekly semaglutide at 2.4mg in adults with overweight or obesity alongside lifestyle intervention

According to the World Health Organization (WHO), approximately 890 million adults were living with obesity in 2022, while the International Diabetes Federation (IDF) estimated that 589 million adults aged 2079 years were living with diabetes globally in 2024, with the number expected to reach 853 million by 2050

They have also become cultural phenomena, fueling countless headlines, celebrity speculation, and fierce debates over cost and access

Yes, under certain circumstances