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This makes S-Acetyl-L-glutathione a promising candidate for conditions involving impaired GSH synthesis, offering a significant advantage in medical research and treatment strategies focusing on oxidative stress and related disorders
They can provide additional support when natural production is insufficient or require an extra boost during increased demand or compromised health
As such, the model was used to simulate how long it would take pharmacologically and toxicologically relevant concentrations of doxorubicin to yield a 70% reduction in GSH concentration, indicative of impaired cellular antioxidant defence, protein binding and cell death 19
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