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If you are deficient in any of these nutrients, direct glutathione supplementation may not be broken down or recycled efficiently

It acts as a cofactor for lysyl oxidase, the enzyme that crosslinks new collagen and elastin into stable matrix

Vitamin E (800 IU daily) has some evidence supporting its use in non-diabetic adults with biopsy-proven NASH, but this is specialist-initiated, off-label use requiring discussion of potential risks, including increased risk of haemorrhagic stroke and prostate cancer with long-term use

As treatment options continue to expand, healthcare providers have an opportunityand a responsibilityto ensure these therapies are used safely, ethically and as part of personalised care