The authors suggest that inhibition of FAO may lead to an overall decrease in cancer cell survival, while an increase in CPT1 activity, such as the PRL-mediated response, may provide a supportive environment for malignant cells 36
Mechanistically, alterations in gut microbial metabolites such as SCFAs could affect the integrity of the BBB, induce systemic endotoxemia, and activate microglia so as to impact disease progression
Over the following decades, studies looked at its role in collagen and elastin support, wound healing, antioxidant activity, inflammatory signaling, and the production of glycosaminoglycans that help keep skin hydrated and firm
Selected Research References Ng FM, Sun J, Sharma L, et al