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Carcinogenesis , 32(4), 545-553
The GLP-1RAs@NPs-WYRGRL precipitate, which was coated with GLP-1RAs and cross-linked with WYRGRL, was obtained
Following a toxic dose of APAP, the conjugation pathways of the liver are overwhelmed and an increased proportion of APAP is metabolized by cytochrome (CYP) P450, predominantly CYP2E1, to the highly reactive metabolite NAPQI (Mitchell et al
This comprehensive characterization is crucial to validate that the affinity reduction is both pH-dependent and does not compromise the intended targeting function
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