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Both approaches work, and the most important factor is consistency rather than precise timing

Long-term impact on total cost of care also remains to be seen. Employer groups are wondering if employees who are taking the drug for diabetes will be on them indefinitely, creating a costly, new, long-term budget concern with lingering questions about any savings from reductions in obesity-related illness

It is the single biggest factor in whether the experience is smooth or rough

This study did not find higher rates of gallstones, often associated with weight loss, with these drugs, and found fewer episodes of ileus, or blocked colon, than expected based on age and other medical conditions