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Its structure incorporates several non-natural amino acid modifications that enhance receptor binding affinity and metabolic stability compared to endogenous ghrelin
7,8,9 The 2024 Dao study of 168 first-trimester GLP-1 exposures and the 2024 Cesta study of 938 periconceptional GLP-1 exposures both found no significant increase in major birth defects
Mozzanica N et al
One study showed decreased levels in post-bariatric surgery patients, but this high-risk group had multiple confounding factors
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