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Yes, you can safely combine these treatments under specialist clinical supervision
Because this mechanism is glucose-dependent (only activated when blood glucose levels are elevated), DPP-4 inhibitors do not carry the risk of hypoglycemia, unlike traditional insulin secretagogues
Your GLP-1 and GIP receptors are already adapted to agonist stimulation, which means the GI adjustment to retatrutide may be less severe than starting from scratch
I tell my patients that the medication is only one-third of the plan
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