\Oral Bioavailability: Can be absorbed orally, with tissue distribution similar to intravenous administration (Animal Study)
Verhaeverbeke, 1997) One trial of predominantly vegetarian families from India (Deshmukh, 2010) One trial of half vegetarians and half vegans whose responses were mixed together (Del Bo, 2019) One trial of B12 supplementation in vegans who werent previously supplementing (Crane, 1998) The dotted lines represent the trial of only vegans (500 g per day by Crane et al.) and the trial of half vegetarians and half vegans (50 g and 2,000/wk by Del Bo, 2019)
Note that due to the relative small size of the rats, rat fistulas regularly appeared as large and complex, and thereby, in this respect, corresponded to the worst presentation in the patients (Klicek et al., 2008
Dose , delivery method (injectable, topical, oral) and goal (skin, hair, healing) must match - get one wrong and the peptide still works , but never quite transforms