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Andrew Huberman: But the point that you're making is a really good one, that the four gram amount is not a threshold based on anything, except the threshold of people's willingness to actually take the stuff

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Dilute with purified water first, if you have sensitive skin

While this increased risk doesn't prohibit GLP-1 users from going under, it forces medical teams to treat these cases with "full stomach" precautions, modifying their anesthesia plans or altering pre-op prep to actively protect your lungs