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Tesamorelin has been developed as a potential treatment for a variety of conditions related to the deficiency of growth hormone, including HIV-related lipodystrophy [1]

The fundamentals matter regardless of medication: Calorie deficit through proper nutrition High protein intake (0.7-1g per pound daily minimum) Resistance training 2-4x weekly Adequate sleep and stress management Sustainable lifestyle changes Medications like retatrutide can be powerful tools, but they work best when combined with the basics

Those patients that have complications that have been shown to be ameliorated by GLP-1-based drugs, and I would say secondary prevention of cardio, of heart attacks for semaglutide

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