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Graphical abstract highlights the role of lipid dysregulation in the pathogenesis of depression, links lipid profile alterations to neuronal dysfunction, stress response, and comorbidities, and proposes diagnosis/treatment targeting lipids

Alternatively, obesity may also promote cholesterol metabolism toward the production of bile acids with the aim of facilitating the absorption of excess body fat [47], in line with our findings

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Additional semaglutide risks include pancreatitis, gallbladder disease, acute kidney injury, and diabetic retinopathy complications in patients with diabetes