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30 According to the Rome IV criteria, a diagnosis of IBS requires recurrent abdominal pain, (on average, at least one day per week during the past three months) with at least two of the following characteristics: related to defecation associated with a change in stool frequency associated with a change in stool appearance As different treatments may be indicated for those with constipation-predominant IBS (IBS-C) versus diarrhea-predominant IBS (IBS-D), knowledge of which subtype a patient experiences can be useful

The maximum dose is 12 mg per week

It has caused misdiagnoses and unnecessary procedures

These blood sugar benefits typically begin within the first week of treatment and reach their peak effectiveness around month three