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K1 cells were again treated with various concentrations of RSL3 (0.0053 M), and Western blot analysis was performed
Treated mice showed increased proportions of larger, healthier muscle fibers and decreased intramyocellular lipid content, indicating enhanced fat oxidation capacity within muscle tissue
Melanotan-1's selectivity for MC1R eliminates most of those off-target effects, which is why clinical trials reported adverse event rates of 812% for nausea with Melanotan-1 versus 3550% for nausea, flushing, and spontaneous erections with MT2
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