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At the same time, Semaglutide can cause diarrhea in some people

Risks Versus Benefits Retatrutide is a novel drug for obesity and metabolic diseases

Progestogen-only pill worsened the HS symptoms, while beneficial effects are exerted for female patients by combined oral contraceptive pills, and anti-androgen agents, such as cyproterone acetate, a competitive antagonist at the androgen receptor, finasteride, an inhibitor of type 5-reductase, the enzyme converting testosterone and its active metabolite 5-dihydrotestosterone, or spironolactone, a potassium-sparing diuretic acting as competitive aldosterone receptor antagonist and exerting weak anti-androgenic effects [82]

They were later FDA-approved for weight loss in 2014