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Over an average follow-up of nearly seven years, the results were striking: for patients whose diabetes was diagnosed within the last 10 years, bariatric surgery slashed the risk of death by 62% compared to GLP-1 drugs (hazard ratio 0.38, 95% CI 0.25-0.58)
941 However, these neuroprotective drugs often fail to achieve the expected therapeutic effect due to poor BBB permeability and short circulatory half-life
In contrast, pharmacologic inhibition of CAT induces apoptosis in cancer cell lines, such as lung and ovarian cancer [45]
It has an acetyl group (COCH3) attached to the sulfur in cysteine of the glutathione molecule
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