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Insulin resistance, as well as the conditions of hyperinsulinemia, hyperglycemia, and elevated free fatty acids, play a substantial role in causing injury to cardiomyocytes, deteriorating their functionality, and leading to myocardial lipotoxicity in individuals with diabetes [88]
Selenium-enriched eggs predominantly provide selenium in organic forms, which exhibit superior absorption and biological efficacy compared with inorganic selenium sources (136)
Clinical Evidence Several clinical trials and studies underscore the cardiovascular benefits of GLP-1 receptor agonists: SUSTAIN-6 Trial : This pivotal trial demonstrated a significant reduction in major adverse cardiovascular events (MACE) among patients treated with GLP-1 compared to placebo
Interestingly, heterozygous KEAP1 mutations frequently occur in lung cancers (Singh et al., 2006
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