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Inhibition of Gln metabolism reduces the frequency of CSCs population in vivo and the rate of tumor growth in mouse models

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Its primary role during pregnancy is to protect cells from oxidative stress and support the body's natural detoxification processes

It was found that GHR expression and its protein level are reduced in the skeletal muscle of ATG7 knockout mice, implying a synchronous relationship between GHR and autophagy (Zecchini et al., 2019)