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In studies examining blood GSH in AD, 7 studies used the Hachiniski Ischaemic Score (HIS 4) to differentiate those with AD from those with potential vascular causes [41, 46, 55, 58, 60, 61, 69], and 5 of those studies further used neuroimaging to support diagnosis [55, 58, 60, 61, 69] (Table 2)