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However, the endogenous antioxidant MnSOD was increased, which may be an adaptation to counteract increased free radicals during ATP synthesis in the OXPHOS complexes

doi:10.1016/j.obpill.2025.100205 Ben-Porat T, Sherf-Dagan S, Ct M, Miner CJ, Buch A

This extended duration enables once-weekly dosing schedules in sustained research protocols and reduces the result variability introduced by more frequent administration windows a key advantage for structured multi-week studies