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Ghasemi A, Amjadi F, Masoumeh Ghazi Mirsaeed S, et al
Top Key Players in the Bacteriostatic Water for Injection Market Pfizer Inc
Research shows that in senescent cells, p53 levels are maintained low through ubiquitination while its pro-apoptotic activity is repressed through nuclear segregation by FOXO4. The peptide's competitive inhibition restores p53 activity by promoting nuclear exclusion, allowing p53 to execute its pro-apoptotic program and eliminate senescent cells through targeted pathway activation
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