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An additional medium change was then accompanied by the addition of toxic concentrations of either NFT (Fig

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(9) In one study on murine models, the authors commented that " CJC-1295 caused an increase in total pituitary RNA and GH mRNA, suggesting that proliferation of somatotroph cells had occurred, as confirmed by immunohistochemistry images

Moreover, we were able to demonstrate that antagonism of the GIPR, but not GLP-1R, completely blocked the ability of either hGIP or tirzepatide to stimulate glucagon secretion (Extended Data Fig