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Given that the kidney-protective effects of SGLT2 inhibitors are independent of glucose lowering [51], DAPA-CKD and EMPA-KIDNEY have included participants both with and without diabetes mellitus (Table 1, Fig
The CaAb-IGF-1 fusion protein had sustained cartilage binding ability and IGF-1 biological activity, promoting cartilage formation in model mice
Additionally, HER2 can be translocated to the mitochondria by the intercourse with mitochondrial heat shock protein-70 (mtHSP70), which negatively controls oxygen consumption and thus enhancing glycolysis (219)
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