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The released drug molecules can then exert their therapeutic effects, such as inducing apoptosis in cancer cells

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In one single-center trial of 72 subjects using a controlled-adverse-environment model, the T4 eye drop did not meet its co-primary endpoints (ocular discomfort and inferior corneal staining) at the primary time point, but it did produce statistically significant improvements on several secondary endpoints, including central and superior corneal staining, with no adverse events reported

Fibroblast growth factor-21 enhances mitochondrial functions and increases the activity of PGC-1 in human dopaminergic neurons via Sirtuin-1