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When To Consult a Doctor While occasional constipation is common and typically not a cause for concern, persistent constipation that significantly impacts your quality of life should be addressed by your doctor, particularly if you've tried over-the-counter remedies like fiber supplements and osmotic laxatives without success

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This requires accepting responsibility for quality verification, reconstitution, and dosing, but provides 65-75% cost savings compared to retail pharmaceutical pricing

The differences were statistically significant at p 0.05 and highly significant at p 0.01