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It temporarily blocks opioid receptors in the brain, which triggers a rebound effect, causing the body to increase its production of endorphins and enkephalinsnatural chemicals that reduce pain, regulate the immune system, and promote healing
It came to a point where they were asked to fast for ten days to clear glucosuria
HPG Axis Suppression by Obesity Leptin resistance and hyperinsulinemia, both features of obesity, suppress GnRH pulsatility at the hypothalamus
Journal of Clinical Endocrinology & Metabolism , 105(4), 1023-1035
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