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On treatment with a bolus of H 2 O 2 (500 M) to induce oxidative stress, the ratiometric imaging of HeLa cells revealed a decrease in the GSH level from 5.0 to 4.1 mM within 90 s (Fig
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Accordingly, we encourage the adoption of GLP-1RA plus SGLT2i combination therapy in patients with T2DM and established atherosclerotic cardiovascular disease (ASCVD) or multiple risk factors for ASCVD (i.e., age 55 years, overweight/obesity, dyslipidemia, hypertension, current tobacco use, left ventricular hypertrophy, and/or proteinuria)
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