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Semaglutide works on one receptor (GLP-1) while tirzepatide works on two receptors (GLP-1 and GIP)

For a beneficiary to qualify, their provider must submit a prior authorization request that attests the beneficiary is being prescribed the drug to reduce excess body weight and ongoing maintenance of weight reduction and that they fall into one of three categories related to BMI and other clinical diagnostic criteria (Figure 3)

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