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P., Carmeli, Y., Cosgrove, S
This difference supports a concept of testable synergy rather than simple redundancy
However, the model concentration of GSH declines in the fasting state about as rapidly as observed experimentally (See Section B, below)
Likewise, the origin of the glutathione that accumulates in this compartment remains unclear, as does whether external factors, such as glutathione-rich diets or direct intake of this compound as an antioxidant supplement, might influence its levels in the tumour microenvironment
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