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Furthermore, BHB influences adipocytes by upregulating uncoupling protein 1 (UCP1) and PR domain containing 16 (PRDM16) via the AMP-activated protein kinase(AMPK)/SIRT1/PGC-1 pathway, resulting in reductions in body weight and lipid levels [112]
This idea is supported by Baek et al, who reported improved cognitive performance in older adults with cognitive impairment that completed 6-week of dual-task resistance band-based RT (3 sets of 10 repetitions, 3 times per week), which involved cognitively stimulating tasks simultaneously during RT (Baek et al., 2024)
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Doi: Costa ACS, Brando AC, Boada R, Barrionuevo VL, Taylor HG, Roth E, Stasko MR et al (2022) Safety, Efficacy, and Tolerability of Memantine for Cognitive and Adaptive Outcome Measures in Adolescents and Young Adults with Down Syndrome: A Randomised, Double-Blind, Placebo-Controlled Phase 2 Trial
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