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As of the 28 January 2025 revision it is indicated not only for glycaemic control in type 2 diabetes, but also to reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes and established cardiovascular disease, and to reduce the risk of sustained eGFR decline, end-stage kidney disease and cardiovascular death in adults with type 2 diabetes and chronic kidney disease
Most Common Early Semaglutide Side Effects and Their Duration Nausea ranks as the most frequently reported side effect, affecting approximately 25% to 35% of patients during the first month
These included nausea, vomiting, diarrhea, constipation, and abdominal pain, and were mainly transient and mild to moderate
Weight loss is most effective when integrated into a lifestyle change rather than relying solely on medication
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