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More recent systematic reviews and meta-analyses published between 2020 and 2022 have broadly confirmed this picture, reporting small, short-term reductions in body weight and body mass index, particularly in older adults and individuals with obesity or metabolic conditions, but with effect sizes that remain clinically modest
A licensed provider then reviews that intake and, using clinical judgment, decides whether treatment is appropriate and which pathway might fit - semaglutide-based or tirzepatide-based
