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Caspase-3 activation is an early event and initiates apoptotic damage in a human leukemia cell line
The amplified fragment from gr knockout mutant using primer pairs gr OF/ gr OR was sequenced to confirm the mutants
Mice were euthanized using gradual-fill CO inhalation in accordance with the AVMA Guidelines for the Euthanasia of Animals (2020), followed by cervical dislocation to ensure complete euthanasia before tissue collection
It works by slowing tyrosinase, the enzyme that triggers melanin production
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