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These new blood vessels can form a target for one of the injection techniques (more later)
This is particularly relevant for metal-containing platforms (for example, ZIF-8), where ion release during degradation may perturb ionic homeostasis and inflammatory signaling, necessitating rigorous extractables and extended biocompatibility testing
For skin and potential GI tract benefits, oral delivery may provide some value, but evidence is limited
Such studies may facilitate the identification of novel therapeutic targets and the development of innovative treatment options
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