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demonstrated that in HepG2 cells, L-carnitine acts as an endogenous histone deacetylase inhibitor, promoting p21Cip1 expression ( In addition, a rat hepatitis-HCC model suggested that L-carnitine might mitigate processes associated with hepatocarcinogenesis, such as oxidative stress, and improve mitochondrial function ( The potential tumor-suppressive effects of L-carnitine provide a unique chemopreventive perspective for long-term MASLD management

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Moosmayer D, Hilpmann A, Hoffmann J, Schnirch L, Zimmermann K, Badock V, et al

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