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Heres how the authors explained this this: in the early stages of the disease, the gut makes a lot of GLP-1 to manage blood sugar
it occurs in fewer than 1% of users and typically presents as severe abdominal pain, elevated lipase enzymes, or persistent vomiting
These data indicate that the weight loss effects of the mGIPR-Ab/GLP-1 peptideantibody conjugate are not exclusively driven by GLP-1R agonism
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