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Animal data is a necessary first step, but its far from sufficient on its own to draw conclusions about a drugs effectiveness and safety in humans

BRIAN: Once you do stop a certain behavior, is there any evidence that the brain will rewire itself in terms of its way that it thinks about addiction

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The patient population is very large, so when you start seeing these types of possible complications or adverse events, they need to be looked at, and theyll likely be added to labeling, Russo added, reiterating that it does not mean that the drugs are unsafe