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In the Phase IIb trial data summarized by Metabolic Pharmaceuticals, participants receiving up to 1 mg/day of oral AOD-9604 for 24 weeks showed no statistically significant changes in fasting glucose, insulin, or IGF-1 compared to placebo [6]

Cell Cycle 12:21632164 Jopling HM, Odell AF, Pellet-Many C, Latham AM, Frankel P, Sivaprasadarao A, Walker JH, Zachary IC, Ponnambalam S (2014) Endosome-to-plasma membrane recycling of VEGFR2 receptor tyrosine kinase regulates endothelial function and blood vessel formation