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Based on clinical trials and FDA labeling, gastrointestinal side effects, including diarrhea, commonly occur early in treatment and with dose increases, then tend to lessen after dose stabilization
Neurosci Biobehav Rev 149:105159 Morshed ASM, Noor T, Uddin Ahmed MA, Mili FS, Ikram S, Rahman M et al (2023) Understanding the impact of acne vulgaris and associated psychological distress on self-esteem and quality of life via regression modeling with CADI, DLQI, and WHOQoL
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