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Key Nutrients Depleted by Corticosteroids Corticosteroids are associated with depletion of multiple nutrients essential for tissue repair, immune defense, and metabolic stability, including: Calcium, vitamin D, magnesium, potassium, zinc, selenium, vitamin C, and protein (1) Mechanisms of Steroid-Induced Nutrient Depletion Calcium & vitamin D: Reduced intestinal absorption and increased urinary loss osteopenia and fracture risk Zinc, selenium & vitamin C: Impaired immune function, delayed wound healing, increased infection risk Protein: Accelerated protein breakdown muscle wasting and connective tissue weakness Magnesium & potassium: Electrolyte imbalance fatigue, weakness, and cardiac rhythm disturbances Why Steroid-Induced Nutrient Depletion Impairs Healing By chronically elevating cortisol signaling, corticosteroids shift the body into a catabolic, stress-dominant state
Its recommended to stay hydrated and avoid excessive sun exposure post-treatment
The lack of tailored standards presents safety and reliability risks for devices manufactured in space
The pharmacokinetics of the sEVs in blood circulation has been generally investigated via intravenous administration (Gudbergsson et al
