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Amylin's primary physiological functions include [11] : Slowing gastric emptying: Delays the rate at which food enters the small intestine, reducing post-meal glucose spikes Controlling glucose metabolism: Reduces inappropriate hepatic glucose output during meals Promoting satiety: Acts on area postrema in the brainstem to reduce food intake In type 2 diabetes, amylin secretion is impaired alongside insulin deficiency, contributing to postprandial hyperglycemia and dysregulated satiety [12]

GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis

This means you feel full for longer, which can help you eat less and lose weight

Effectiveness and safety of semaglutide for weight loss in patients with inflammatory bowel disease and obesity