doi:10.2174/157015909787602788 Kappos L, Gold R, Miller DH, Macmanus DG, Havrdova E, Limmroth V, Polman CH, Schmierer K, Yousry TA, Yang M, Eraksoy M, Meluzinova E, Rektor I, Dawson KT, Sandrock AW, ONeil GN, BG-12 Phase IIb Study Investigators (2008) Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study
To account for bimodal expression of insulin and glucagon hormones in the same cell, approximate counts per million thresholds for each marker gene were used before classifying cell types
In a rat model, LC lowered liver enzyme activity, oxidative stress, and thioacetamide and tilmicosin-induced damage (Aboubakr et al., 2020)
Additional concerns include potential kidney problems in patients with existing kidney disease and acute kidney injury in severe dehydration cases