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Whats more, the deficiency of GPX4 did not enhance the ER stress signal induced by H 2 O 2 , while in the absence of SELS, the lack of GPX4 would cause further deterioration of the ER stress signal
Efficacy, safety and impact on -cell function of dipeptidyl peptidase-4 inhibitors plus metformin combination therapy in patients with type 2 diabetes and the difference between Asians and Caucasians: a meta-analysis
Xie X et al
They act on two different receptors that converge on the same outcome, which is why pairing them produces a more complete signal than either one alone
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